Korean: 테트라아미노피리미딘설페이트 · CAS 5392-28-9 · Functions: hair dyeing
No specific rule on file.
Restricted Annex III/200 (2)
Maximum: (b) 3,4% (calculated as sulphate)
Conditions: Product type: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products (c) Products intended for colouring eyelashes (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate) (c) Professional use
Required label warning: (a) To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (c) As from 3 March 2018, to be printed on the label: The mixing ratio. “This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. For professional use only. Rinse eyes immediately if product comes into contact with them”.
Source: EU CosIng — Annex III · checked Oct 17, 2026
Restricted Annex III/200
Maximum: (b) 3,4% (calculated as sulphate)
Conditions: Product type: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products (c) Products intended for colouring eyelashes (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate) (c) Professional use
Required label warning: (a) To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (c) As from 3 March 2018, to be printed on the label: The mixing ratio. “This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. For professional use only. Rinse eyes immediately if product comes into contact with them”.
Source: EU CosIng — Annex III · checked Oct 17, 2026
No specific rule on file. The FDA regulates few cosmetic ingredients by name; no rule does not mean approval.
How Tetraaminopyrimidine Sulfate is treated in 3 more markets, from the overseas cosmetic regulation database compiled by Korea's MFDS. Always confirm with the regulator of that country before selling there.
| Market | Status | Conditions |
|---|---|---|
| CN China | Restricted | MFDS summary (Korean): * 【화장품 중 최대사용농도】 배합한도 (산화형 염색제) : 2.5% * 【화장품 중 최대사용농도】 배합한도 (비산화형 염색제) : 3.4% |
| AS ASEAN (10 countries) | Restricted | MFDS summary (Korean): * 【Restrictions】 Field of application and/or use : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. * 제한 【사용 범위】 : (a) 산화형 염모제에 염색 성분으로 (b) 비산화형 염모제에 염색 성분으로 눈썹이나 속눈썹의... |
| TW Taiwan | Restricted | MFDS summary (Korean): ※ 染髮、脫色、脫染及燙髮產品之應刊載之注意事項，應依衛生福利部公告刊載之。 ※ 染髮產品之限量標準：係指該成分依產品使用說明書混合後之最高允許使用量。 ※ 化粧品之外包裝或容器，應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者，應於標籤、仿單或以其他方式刊載之。 ※ 本表所稱之口腔製劑，包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。 ※ 化粧品宣稱效能者，須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。 * 단서조항 : ※ 染髮、脫色、脫染及燙髮產品之應刊載之注意事項，應依衛生福利部公告刊載之。 ※... |
Source: MFDS cosmetic ingredient use restrictions — overseas regulations · checked Oct 17, 2026
TETRAAMINOPYRIMIDINE SULFATE 테트라아미노피리미딘설페이트
Information only, not medical advice. Rules change — always check the linked official source. If you are pregnant, have a skin condition or allergies, ask a dermatologist or pharmacist.
In the EU's CosIng records it is listed as “Restricted” (EU CosIng — Annex III). The maximum allowed is (b) 3,4% (calculated as sulphate). A restricted ingredient is allowed within the stated conditions.
We found no specific rule for it in Korea's MFDS records. That is not an approval or a safety statement.
We found no specific rule for it in the FDA's records. That is not an approval or a safety statement.
The EU's CosIng inventory lists its functions as: hair dyeing.
Korea's MFDS standard Korean name is 테트라아미노피리미딘설페이트.
CAS 5392-28-9 (from official records).